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Post if you have tried sublingual B6.
For those who don't know what it is, it's a special form you put right on your tongue to dissolve directly into your bloodstream.
Recently, there was a B12 infomercial I watched for a few seconds. They were saying how 90 or 80 percent of the vitamin isn't absorbed when you swallow it as a pill. Wondering if this will help...
Hmmm it would probably be awesome to wake up after 6 hours or so and then take that. I will have to check the pharmacy I work at to see if they carry those.
Just a lil background information:
Sublingual absorbtion is best for drugs taken in the microgram range.
B12 is usually used in the range of 100-1000 micrograms (1,000 being a very huge dose) and you only really need 2-6 micrograms to enter the blood stream to prevent B12 deficiency. B12, as you said, is poorly absorbed by the intestines- especially as you get older. This is why its often supplied as injections to the elderly and more recently sublingual tabs for the masses.
B6 is usually used as 25-100 mg pills (thats 25,000-100,000 micrograms), thats a ton to absorb through the oral mucosa. It is generally absorbed by the intestines just fine. Moreover if its supplied as pyridoxine hydrochloride (as it usually is when in pill form) getting it into your blood doesnt make it immediatly take effect anyway because it must be converted to pyridoxal by the liver (ie. chewing a normal pill isnt the same as a sublingual tab from a legitimate manufacturer... just so you know :wink: ).
...some pydridoxal-5'-phosphate is available on the market, this includes the legitimate sublingual tabs (read the lables).
With that said, I too would be quite interested if a sublingual B6 tab notably effects dreams if taken in an interrupted sleep cycle. Many people who take B6 pills border on the toxic dose of the vitamin, sublingual tabs just supply ~17 mg so should be safer.
...?
I keep sublingual melatonin/ B6 (dose - 2.5 mg melatonin; 335 mcg B6) to help with sleep when I think I might have trouble. Once I took some after waking up in the middle of the night and I subsequently semi-successfully WILD-ed. Unfortunately this has not worked again. I don't take melatonin every night because doing that can suppress the brain's natural production; I try to save it for when I need it.
Anyway, it may have been the pizza or whatever I had for dinner, or just the right timing. Hard to say.
I ordered a bottle of sublingual B6 today. For some reason, the only dosage available is 25mg. Probably because it's so much stronger.
I read some research showing that only around 1% enters your bloodstream with a pill. If sublingual, then 99% more enters your bloodstream. Read up on it for a better explanation.
In other words, sublingual is not only faster, but much more efficient. Can't wait to see how well it works 8)