Sure it does. Reality as we perceive it is for the most part an illusion. For example, the distance from the nucleus of an atom to its first ring of electrons is proportional (approximately) to the distance from the head of a pin sitting in the middle of a football stadium to the furthest bleacher. This means that the physical world is mostly empty space.
That means that our perception of physical reality is literally an illusion to our senses.
You take this fact, and couple it with Quantum Mechanics' theory of the behavior of electrons (that says electrons behave as both waves and particles), and you are left with the assumption that reality is really just one, interconnected, vibrating principle that has different manifestations across the electromagnetic spectrum.
Now, this is all theory. The experiments that this theory is based off of may in fact be invalid. When measuring things as small as atoms, it's entirely possible that there is experimental error we don't even know about. But the
current science points towards some web of reality that is nothing like what we perceive. Like we are comparable to molecules of H20 within the ocean -- we appear separate but we can prove empirically that we're all connected and moving within waves.
I don't know how this connects with 2012. Personally, I think that 2012 and this new era of change has everything to do with the intelligence revolution. Previously, Humankind would manipulate the earth and the environment to serve its purpose. We've learned that this has serious negative consequences (Global Warming, Nuclear weaponry, etc etc). But now, we are learning to consciously co-create, to build in
harmony with the environment through chemical and environmental engineering. I think of this IBM commercial:
http://www.youtube.com/watch?v=w70c4E-wURU
No longer are we taking advantage of nature, raping it for our purposes without a thought for long term consequences -- we're using the qualities that set us apart from animals (our ability for mathematics and abstract, analytical thought) to create a better, more sustainable planet.
Assuming that we won't experience some kind of mystical revolution or some sort of psychic flowering where we can time travel and move objects with our minds, I think that this Intelligence Revolution is the closest match to the Mayan "higher consciousness" we will experience.