The full effect of these different drugs on the mind including subconsious is generally not known. This means the damage it does to you, and also the benifits of the drugs are not known. It is a big mess. Just a mixture of generally random chemicals created from ignorance. Research is limited due to the mess of our society and it's structure.

Since everyone reacts in their own way to these drugs and that our full scope of reality is not understood. This adds to the confusion.

I believe it is possible to make a drug that would open up our higher senses. To help us spiritually and physically. Help us in many different ways. A drug that benifits lucid dreaming. Drugs for recreation without damage of the mind. Drugs that heal disease. the sky is the limit. You have seen some of the effects of drugs that are made from ignorance. If these resources of nature could be cultivated and created for the proper reason, under a higher spiritual understanding. much could be achieved and realized in this area.

The effects are unlimited in what could be created. The only thing is it would take is intense reseach and desire. A total unraveling of society as we know it. Humanity does not have the resources and is in no condition to advance in this area any time soon.

If humanity was mature enough to develop these drugs for these purposes, we would also have gathered sufficent wisdom and spiritual understanding that would reveal the true nature of reality and purpose. And therefore the need for drugs would become less important as we would become in control of our own minds and advance ourselves.

However everything including technology can be used positivly or negativly acording to our understanding and choices about how we are use it.

For example you can use technology for the sole purpose of advancing yourself spiritually. or you can use it to make your life easier. Or you can use it to exploit and enslave.

it's the same thing with drugs or anything else.

We are spiriutal beings having an experience and our choices and experience will lead to whatever result we desire or choose.

I know that is a very vague and diverse answer to the question. But the answer is simply not known and this is the best way I know how to answer that.