In dreams I've done pretty much every common drug. In my experience, only hallucinogenic effects are ever similar to a real drug's effect, though usually exaggerated, or just like being really, really drunk instead. Just as often though, I'll take a whole lot of a drug, or drink copious amounts of booze in a dream and feel nothing. Onset of effects always seems to be immediate too, which makes no sense for most things.
It's actually a dream sign when I take substances and they don't affect me normally.
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