If money is no issue at all I truly would have to say that most of the NVIDIA 8800's are the way to go. The architecture of the 8800 series far surpasses that of the previous 7900 series. I have a BFG 7900GTX and it can still dominate most games, but it really doesn't even pale in comparison to the real power behind NVIDIA's 8000's and such. I believe the 8800 Ultra just came out, that thing will handle it all and then some. Good luck looking around.