Most spyware runs independent of the browser. Do Ctrl+Alt+Del and look at your processes. There is a tab for RAM usage somewhere. Take a screenshot, then leave your computer for ten minutes and compare the resources. If the computer was just sitting there then the amount of RAM used by the processes shouldn't have changes significantly. If something jumped way up, google the name of it and I'm sure you will find other cases of the same bot infecting other people's computer, plus the solution for it.