The chemicals of weed are not recreated in your mind, so that's not entirely true. The brain can only produce chemicals the brain has, so yes, you can experience several drug side effects (while in the dream, perhaps indistinguishable from the drug itself), but you cannot produce the drug's chemical byproducts.
I've never experienced a drug effect while waking. I've experienced several lingering emotions, tastes, and even physical feelings while waking, so I bet a drug feeling could ooze over into wakefulness, too.
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