Hello theshirecat,
thanks for your message. I take choline supplements quite often as nootropics and experience no ill effect. As you note, our brains seek to maintain homeostasis and, in the absence of an AChEI like Galantamine or Huperzine, AChE will remove excess ACh from the system. Yuschak suggests using Piracetam to speed up the process as Piracetam is observed to increase the function of ACh with certain receptors. I think of it as "mopping up" excess ACh. I cannot recall if Yuschak mentions this but if one takes Piracetam (or other Racetams) with little or no ACh availability, a common side effect is the "icepick headache" - which is, as the name would imply, quite uncomfortable, but easily remedied by adding an ACh source. Lastly, while Yuschak only mentions Piracetam, in recent years a number of other Racetam variants have come on stream, some of which are more efficient than Piracetam and require smaller amounts for similar results.
https://en.wikipedia.org/wiki/Racetam
Enthusiasts would have us believe that each of these variants has a slightly different effect on cognition, memory, mood, etc.
As always, before taking any supplement it recommended to have a discussion with a trusted physician regarding benefits, side effects, or other concerns.
Wishing you all a dreamy weekend!
William
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