I get that ALL the time! I'd say about once or twice a day. Such a pain in the bum! =[
I then end up having to exit FF completely and everything is normal again.
So, no! You're not the only one!
What extensions are you running? It might have to do with that. Right now, I've only got Greasemonkey, Tab Mix Plus and IE Tab installed.
EDIT: er wait, also have ad-block, flashblock, long titles, video downloader (disabled) and Vimperator (also disabled)...
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