We use do use all regions and areas of the brain, only not all at the same time. Much of awareness does take place on the subconscious level, so the brain is perceiving and processing a large amount of information, but only passing on the relevant bits to our conscious mind. Even if there were a magic pill to allow you to perceive "everything", it would be a matter of bringing whatever is in your subconscious mind to the conscious, not activating unused portions of the brain. Even if this were a possibility, I'm not sure it would be a good idea for daily functioning. If you've ever taken hallucinogens, you know that something like this can happen to your awareness while under the influence. Being completely absorbed in every detail, sound, energy wave is a great experience and possibly conducive to spiritual insight, but its impossible to function when you can't even stand up because your amazed at the level of detail of your experiencing from the floor.
Of course someone can loose a portion of their brain and still function (depending on what region they loose); other areas of the brain will take on the functions of the missing portion. The same way if someone looses an arm, they learn to compensate by using other limbs to take on the same functions as the missing one. Often, though, this results in a personality change or learning or memory disability.
Anyway, allowing access to the subconscious mind in a conscience way, is essentially what lucid dreaming does, no magic pill needed.
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