depends on your goal. you could make it up as you go along but better to have pre-planned things you wanna do. I "wasted" my first one on flying and "natural desires", will use the next one for religeous matters like chanting a buddhist mantra and going into lotus pose and conversing with the buddha, but that's just me. You should use it for anything that you want to do but can't do in real life. Imagine yourself as Neo in the matrix at the moment of his 'awakening'- what do you do?