I've only ever tried it once, but LSD was a very liberating experience for me. I was in my friend's basement with him and another person. We took two hits each.
It was as though the world had ended thousands of years ago and we were burried by weather many miles underground. Everyone and everything I knew outside of the basement were ancient memories. The basement was the last room in the universe. It felt like I would be there for all eternity and it didn't matter one bit. Very calming experience.
Also, the site of my friend standing, looking at the dawn through the basement window would've made the perfect album cover!